Fighting Depression During Cancer: The Power of Exercise

For individuals facing cancer, managing side effects and maintaining mental well-being are critical. A growing body of research points to aerobic exercise as an effective intervention for depression during and after cancer treatment.

A new study published in JAMA Open Network analyzed data from previous clinical trials and found that aerobic exercise significantly reduced depressive symptoms in cancer patients, both in the short-term (within 1 month) and long-term (6-12 months). Aerobic exercises include activities that increase heart rate and breathing, such as walking, running, cycling, and swimming.

Dr. Larissa Nekhlyudov, an ASCO expert, notes, “Aerobic exercise may improve depression for patients living with and beyond cancer. However, the benefits are sustained when exercise is continued.”

Depression in Cancer Patients: Depression is a prevalent concern, affecting approximately 1 in 4 cancer patients. Identifying the signs – persistent sadness, loss of interest, fatigue, cognitive difficulties – is crucial for timely intervention.

Mechanisms of Action: Exercise stimulates the release of endorphins, which have analgesic and mood-enhancing effects. Furthermore, aerobic exercise offers additional health benefits, including reduced risk of obesity, heart disease, and diabetes.

Clinical Recommendations: Before initiating an exercise program, patients should consult with their healthcare providers to ensure safety and appropriateness. If aerobic exercise is contraindicated, alternative physical activity options and referrals to physical or occupational therapy should be considered.